Male body as opposed to the female is not able to independently produce the female sex hormone (by the way women are unique, because only their body is able to independently produce and male and female sex hormones – estrogen, testosterone).
Estradiol in the male female sex hormones act only through their conversion from testosterone, to be entirely accurate, it is obtained in this way only one hormone, estradiol, the most powerful of the list of estrogen. This transformation becomes possible only with the participation of special substances – enzymes, bearing the name aromatoze. The process of conversion is called aromatization. Estradiol is present in the blood of all men without exception. The disadvantage estrodiola actually like its excess leads to a reduction of the synthesis of natural testosterone. Estradiol also has a positive effect on the mood of the men in his tone and in fact the success of training. But all this becomes possible only when the normal level of this hormone in the blood. If you violate the same balance between estradiol and testosterone occurs the process of aromatization.
Antiestrogens are divided according to their characteristics and properties of the two groups. The first is an aromatase inhibitor. The second is the estrogen receptor blockers. In the first case, aromatase inhibitors are attached to the enzyme aromatase, just as testosterone and therefore reduce the amount of these enzymes, so a minimum and reduce the risk of developing aromatization. Blockers are also quite different, they are attached to estrogen receptors, do not activate them, but quite the contrary, begin to act, creating noise and interfering estrodiol perform its functions. That is anti-estrogens simply stop conversion of testosterone to estradiol, and estradiol in the second case simply ceases to act or is blocked.
Arimidex is probably the most effective and most expensive anti-estrogen. Arimidex is an aromatase inhibitor and very powerful one, even half a milligram dosage of the drug are sufficiently able to deal with aromatization in most cases. The exception will be receiving particularly high doses of aromatizable steroids, in this case you will need doses greater than 1 mg.
Clomid (clomiphene citrate)
The main feature of Clomid is its versatility, he not only excels at blocking aromatase, but also able to restore the level of luteinizing hormone in men. Clomid is in contrast to most anti-estrogens, can, in some cases even have to take throughout the course of steroid. The average daily dose is 50 mg, ie one tablet, in critical situations, the dosage can be increased by half.
In its structure and properties of Nolvadex (Tamoxifen) is similar to other drugs, namely Clomiphene. It is similar because there are differences, for example, Nolvadex is the more potent drug, but in contrast to Clomiphene, it does not affect the levels of the hormone LH. Another feature of the drug lies in its strong anti-estrogenic effects on the liver and as a consequence of reduced levels of insulin-like factor in the synthesis of IGF-1, as you realize this is a negative feature. The usual daily dose of the drug to be in the region of 20 to 40 mg, it is recommended taking the minimum specified dose, as Nolvadex is a rather powerful steroids.
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